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Ph.D., Psychology
University of Massachusetts, Amherst

1982

1978

B.A., Psychology, Summa Cum Laude
University of South Florida, Tampa

Research Interests

My research focuses broadly on neuroimaging and, more recently, transcranial magnetic stimulation methods to investigate neural correlates of behavior. Some specific areas of interest are: The contributions of the cerebellum, and cerebro-cerebellar circuits, to cognition. Aging effects on awareness and cerebro-cerebellar function.  Integration of transcranial magnetic stimulation with functional MRI to assess which sites of activation are necessary to performance. Clinical applications of functional MRI, including characterization of altered brain activation due to disease, surgical planning, and diagnosis. Methodological aspects of functional MRI, such as estimating statistical power for group analyses.

Current Projects

PRINCIPAL INVESTIGATOR

1) fMRI and TMS Analysis of Cerebellar Cognitive Function

    NIMH R01 MH060234

2) fMRI Analysis of Aging and Awareness in Conditioning

    NIA R01 AG21501

CO-INVESTIGATOR

1) Brain Activation During Sexual Arousal (Dr. Bruce Arnow, P.I.)

Brewer, J. B., Zhao, Z., Desmond, J. E., Glover, G. H., & Gabrieli, J. D. E. (1998). Making memories: Brain activity that predicts how well visual experience will be remembered. Science, 281, 1185-1187.

Desmond, J. E., & Fiez, J. A. (1998). Neuroimaging studies of the cerebellum: Language, learning and memory. Trends in Cognitive Sciences, 2, 355-362.

Desmond, J. E., Gabrieli, J. D. E., & Glover, G. H. (1998). Dissociation of frontal and cerebellar activity in a cognitive task: Evidence for a distinction between selection and search. Neuroimage, 7, 368-376.

Desmond, J. E. & Chen S. H. A. (2002). Ethical issues in the clinical application of fMRI: Factors affecting the validity and interpretation of activations. Brain and Cognition, 50, 482-497.

Desmond, J. E., & Glover, G. H. (2002). Estimating sample size in functional MRI (fMRI) neuroimaging studies: Statistical power analyses.  Journal of Neuroscience Methods, 118, 115-128.

Desmond, J. E., Chen, S. H., DeRosa, E., Pryor, M. R., Pfefferbaum, A., & Sullivan, E. V. (2003). Increased frontocerebellar activation in alcoholics during verbal working memory: an fMRI study. Neuroimage, 19, 1510-1520.

Chen, S. H. A. & Desmond, J. E. (2005) Cerebro-cerebellar networks during articulatory rehearsal and verbal working memory tasks. Neuroimage, 24, 332-338.

Chen, S. H. A., & Desmond, J. E. (2005). Temporal dynamics of cerebro-cerebellar network recruitment during a cognitive task. Neuropsychologia, 43, 1227-1237.

Kirschen M. P., Chen, S. H. A., Schraedley-Desmond P., & Desmond J. E. (2005). Load and practice dependent increases in cerebro-cerebellar activation in verbal working memory: An fMRI study. Neuroimage, 24, 462-472.

Desmond, J. E., Chen, S. H. A., & Shieh PB. (2005). Cerebellar transcranial magnetic stimulation impairs verbal working memory.  Annals of Neurology, 58, 553-560.

Kirschen, M.P., Davis-Ratner, M.S., Jerde, T.E., Schraedley-Desmond, P. and Desmond, J.E., Enhancement of phonological memory following Transcranial Magnetic Stimulation (TMS) (2006), Behavioural Neurology, 17, 187-194.